Description

2-(3,3-Dimethylbicyclo[2.2.1]Hept-2-Ylmethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and a versatile organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex carbon-carbon bonds. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex, sterically hindered biaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific boronic ester functionalities.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is critical.
• Catalyst & Ligand Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new synthetic routes in organic chemistry laboratories worldwide.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Product Name	2-(3,3-Dimethylbicyclo[2.2.1]Hept-2-Ylmethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073355-27-7
Molecular Formula	C₁₆H₂₇BO₂
Molecular Weight	262.20 g/mol
Synonyms	2-[(3,3-Dimethyl-2-norbornanyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-((3,3-Dimethylbicyclo[2.2.1]heptan-2-yl)methyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3,3-dimethyl-2-norbornanylmethyl)boronate; Norbornane-derived pinacol boronic ester; (3,3-Dimethyl-2-norbornanylmethyl)boronic acid pinacol ester; Boronic acid, B-[(3,3-dimethylbicyclo[2.2.1]hept-2-yl)methyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our production of 2-(3,3-Dimethylbicyclo[2.2.1]Hept-2-Ylmethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified by advanced analytical techniques including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.