Description

2-[3-(2-Hydroxyphenyl)Propyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, organoboron building block featuring a phenolic hydroxyl group, which is critical for advanced synthetic chemistry. This compound matters because it serves as a versatile intermediate for constructing complex molecules via cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient synthesis of pharmaceuticals and organic electronic materials. Industries such as pharmaceutical R&D, agrochemical development, and materials science require this specific boronate ester for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific phenolic-boronate structures.
• Material Science: Serves as a monomer or precursor in the development of organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodology development and constructing complex molecular architectures.
• Ligand & Catalyst Development: The phenolic group allows for chelation, making it useful in designing novel ligands for metal catalysts.
• Polymer Chemistry: Can be incorporated into polymer backbones to introduce boronate or phenolic functionalities for specialty polymers.

Basic Information

Product Name	2-[3-(2-Hydroxyphenyl)Propyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073355-25-5
Molecular Formula	C₁₅H₂₃BO₃
Molecular Weight	262.15 g/mol
Synonyms	2-(3-(2-Hydroxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Hydroxyphenyl)propyl Pinacol Boronate; 3-(2-Hydroxyphenyl)propyl-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 2-(3-(2-Hydroxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-(2-Hydroxyphenyl)propyl)boronate; 2-Hydroxyphenylpropylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-[3-(2-Hydroxyphenyl)Propyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and production use. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.