Description

2-(4-tert-Butylphenyl)Ethylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound matters as a critical building block in modern cross-coupling reactions, enabling the efficient construction of complex organic frameworks. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and organoboron compounds, essential for creating biaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing sterically hindered biphenyl or terphenyl motifs.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Chemical Biology & Probe Development: Useful for incorporating boronic acid ester functionalities into molecules for sensing, labeling, or as protease inhibitors.
• Scale-up and Process Chemistry: Suitable for transitioning from laboratory-scale discovery to pilot plant and commercial manufacturing of fine chemicals.

Basic Information

Product Name	2-(4-tert-Butylphenyl)Ethylboronic Acid Pinacol Ester
CAS No.	1073355-22-2
Molecular Formula	C₁₈H₂₉BO₂
Molecular Weight	288.23 g/mol
Synonyms	2-[2-(4-tert-Butylphenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(4-(tert-Butyl)phenyl)ethyl)boronic acid pinacol ester; 4-tert-Butylphenethylboronic acid pinacol ester; 2-(4-tert-Butylbenzyl)ethylboronic acid pinacol ester; tert-Butylphenyl Ethyl Boronate Pinacol Ester; B-[2-(4-tert-Butylphenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-tert-Butylphenyl)Ethylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.