Description

3-Acetoxy-4-Methoxycarbonylphenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected boronic acid building block, offering enhanced stability and solubility for advanced coupling reactions. It is primarily required by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key protected precursor for introducing the phenylboronic acid moiety into complex molecular architectures under palladium catalysis.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl systems common in drug molecules.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the boronic acid functionality is essential.
• Material Science & OLED Development: Acts as a building block for creating organic electronic materials, such as ligands for metal complexes or direct components in emissive layers.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and tags that leverage boronic acid chemistry for sensing or binding applications.
• Scale-up Process Chemistry: The pinacol ester protection offers improved handling and storage characteristics, making it suitable for process optimization and pilot-scale synthesis.

Basic Information

Product Name	3-Acetoxy-4-Methoxycarbonylphenylboronic Acid, Pinacol Ester
CAS No.	1073355-18-6
Molecular Formula	C16H21BO6
Molecular Weight	320.15 g/mol
Synonyms	(3-Acetoxy-4-(methoxycarbonyl)phenyl)boronic acid pinacol ester; Methyl 2-acetoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Acetoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Boronic acid, B-[3-(acetyloxy)-4-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester; 3-Acetoxy-4-methoxycarbonylbenzeneboronic acid pinacol ester; CAS 1073355-18-6
EINECS	Contact for details

Quality Control

Our 3-Acetoxy-4-Methoxycarbonylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.