Description

2-(1,1-Diethoxyethyl)Pyridine-3-Boronic Acid Pinacol Ester is a sophisticated, multi-functional organoboron building block designed for advanced synthetic chemistry. Its molecular architecture, featuring both a protected aldehyde equivalent and a stabilized boronic ester, makes it a versatile intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research scientists and process chemists in pharmaceutical R&D and fine chemical synthesis who require high-purity, reliable reagents for cross-coupling and multi-step transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex pyridine and substituted pyridine cores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing coupling partner for forming carbon-carbon bonds with aryl/heteroaryl halides, enabling the construction of biaryl systems.
• Ligand and Catalyst Development: Used in the preparation of novel nitrogen-containing ligands for transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) where specific nitrogen-boron functionalities are required.
• Agrochemical Synthesis: Acts as a building block for developing novel crop protection agents with enhanced efficacy.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying biological pathways and target engagement.

Basic Information

Product Name	2-(1,1-Diethoxyethyl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1073355-12-0
Molecular Formula	C17H28BNO4
Molecular Weight	321.22 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1,1-diethoxyethyl)pyridine; 2-(1,1-Diethoxyethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine-3-boronic acid, 2-(1,1-diethoxyethyl)-, pinacol ester; 2-(1,1-Diethoxyethyl)-3-pyridinylboronic acid pinacol ester; (2-(1,1-Diethoxyethyl)pyridin-3-yl)boronic acid pinacol ester; Boronic acid, B-[2-(1,1-diethoxyethyl)-3-pyridinyl]-, 1,1,1',1'-tetramethyl-2,2'-bi-1,3,2-dioxaborolane-4,4'-diyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(1,1-Diethoxyethyl)Pyridine-3-Boronic Acid Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials undergo comprehensive analytical characterization, including NMR (1H, 13C, 11B), HPLC, and GC analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.