Description

3-(Tetrahydrofurfurylaminocarbonyl)Benzeneboronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its stability and reactivity, making it an essential reagent for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. This compound is specifically designed for use by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where precise molecular construction is paramount. CAS No. 1073355-06-2.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients for crop protection products.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Employed in the development of boronic acid-based sensors and probes for detecting biological analytes.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential raw material for fine chemical producers offering bespoke synthesis services.

Basic Information

Product Name	3-(Tetrahydrofurfurylaminocarbonyl)Benzeneboronic Acid Pinacol Ester
CAS No.	1073355-06-2
Molecular Formula	C₁₈H₂₆BNO₄
Molecular Weight	331.22 g/mol
Synonyms	3-[(Tetrahydrofuran-2-ylmethyl)carbamoyl]phenylboronic acid pinacol ester; [3-[[(Tetrahydro-2-furanylmethyl)amino]carbonyl]phenyl]boronic acid pinacol ester; 3-(N-Tetrahydrofurfurylaminocarbonyl)phenylboronic acid pinacol ester; 3-Carbamoylphenylboronic acid pinacol ester, N-tetrahydrofurfuryl derivative; Boronic acid, B-[3-[[(tetrahydro-2-furanylmethyl)amino]carbonyl]phenyl]-, 1,1-dimethylethyl ester; (3-((Tetrahydrofurfurylamino)carbonyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-(Tetrahydrofurfurylaminocarbonyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.