Description

5-Aminopyridine-3-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediates: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by constructing heterocyclic scaffolds.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	5-Aminopyridine-3-Boronic Acid, Pinacol Ester
CAS No.	1073354-99-0
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	5-Amino-3-pyridineboronic acid pinacol ester; 3-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-Amino-3-pyridylboronic acid pinacol ester; 3-Pyridineboronic acid, 5-amino-, 1,1-dimethylethyl ester; 5-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol (5-Aminopyridin-3-yl)boronate; 1073354-99-0
EINECS	Contact for details

Quality Control

Our 5-Aminopyridine-3-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.