Description

5-Benzothiazole Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel benzothiazole-containing molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing the benzothiazole scaffold, which is prevalent in compounds with diverse biological activities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the benzothiazole moiety for enhanced efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED emitters and charge-transport materials, where precise molecular architecture is required.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the development of fluorescent probes or enzyme inhibitors for diagnostic and research applications.
• Cross-Coupling Reactions: Specifically designed as a stable, air-handleable reagent for palladium-catalyzed Suzuki-Miyaura couplings with various aryl/heteroaryl halides.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis to create diverse compound libraries for screening in hit identification and lead optimization campaigns.

Basic Information

Product Name	5-Benzothiazole Boronic Acid Pinacol Ester
CAS No.	1073354-91-2
Molecular Formula	C₁₃H₁₆BNO₂S
Molecular Weight	261.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzothiazole; Benzothiazol-5-ylboronic Acid Pinacol Ester; 2-(Benzothiazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Benzothiazoleboronic Acid Pinacol Ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzothiazole
EINECS	Contact for details

Quality Control

Our 5-Benzothiazole Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.