Description

E-2-(3,5-Dimethoxyphenyl)Vinylboronic Acid Pinacol Ester is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex, functionalized organic molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds for constructing complex biaryl and styrenyl structures in medicinal chemistry.
• Agrochemical Synthesis: Serves as a precursor in the development of new active ingredients for crop protection products.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Process Chemistry & Scale-up: Supports the development of robust, scalable synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	E-2-(3,5-Dimethoxyphenyl)Vinylboronic Acid Pinacol Ester
CAS No.	1073354-86-5
Molecular Formula	C16H23BO4
Molecular Weight	290.16 g/mol
Synonyms	(E)-2-(3,5-Dimethoxyphenyl)ethenylboronic acid pinacol ester; trans-2-(3,5-Dimethoxystyryl)boronic acid pinacol ester; 2-(3,5-Dimethoxyphenyl)vinylboronic acid pinacol ester; (E)-2-(3,5-Dimethoxystyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[2-(3,5-dimethoxyphenyl)ethenyl]-, 1,1-dimethylethyl ester; 1073354-86-5; (E)-3,5-Dimethoxystyrylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our E-2-(3,5-Dimethoxyphenyl)Vinylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio)	≥ 98:2 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.