Description

6-(4-Fluorophenyl)Pyridine-3-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Cross-Coupling Reactions: The primary application is in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aryl groups.
• Chemical Library Development: Employed in medicinal chemistry for the parallel synthesis and diversification of compound libraries for high-throughput screening.
• Ligand Synthesis: Useful for preparing specialized bidentate or polydentate ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	6-(4-Fluorophenyl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1073354-81-0
Molecular Formula	C₁₇H₁₉BFNO₂
Molecular Weight	299.15 g/mol
Synonyms	[4-Fluoro-6-(4-fluorophenyl)pyridin-3-yl]boronic acid pinacol ester; 6-(4-Fluorophenyl)-3-pyridineboronic acid pinacol ester; (6-(4-Fluorophenyl)pyridin-3-yl)boronic acid pinacol ester; Pinacol 6-(4-fluorophenyl)pyridine-3-boronate; 6-(p-Fluorophenyl)nicotinic acid boronic ester; B-[6-(4-Fluorophenyl)-3-pyridinyl]boronic acid pinacol ester; CAS 1073354-81-0
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.