Description

1-tert-Butoxycarbonyl-3,5-Dimethylpyrazole-4-Boronic Acid, Pinacol Ester is a high-purity, protected boronic ester building block essential for modern synthetic chemistry. This compound is valued for its stability and reactivity, serving as a key intermediate in the construction of complex molecules through cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, agrochemical development, and advanced materials science.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heteroaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Proteomics: Useful for synthesizing molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized, high-value fine chemicals.

Basic Information

Product Name	1-tert-Butoxycarbonyl-3,5-Dimethylpyrazole-4-Boronic Acid, Pinacol Ester
CAS No.	1073354-70-7
Molecular Formula	C16H27BN2O4
Molecular Weight	322.21 g/mol
Synonyms	Boc-3,5-Dimethylpyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-[(2-methylpropan-2-yl)oxycarbonyl]-3,5-dimethyl-1H-pyrazole; 1-(tert-Butoxycarbonyl)-3,5-dimethyl-1H-pyrazole-4-boronic acid pinacol ester; 1-Boc-3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 3,5-Dimethyl-1H-pyrazole-4-boronic acid, 1-(1,1-dimethylethyl) ester, pinacol ester; 1-N-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester; 4-Borono-3,5-dimethyl-1H-pyrazole-1-carboxylic acid tert-butyl ester pinacol cyclic ester.
EINECS	Contact for details

Quality Control

Our 1-tert-Butoxycarbonyl-3,5-Dimethylpyrazole-4-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and hydrolysis. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.