Description

trans-2-(3,5-Difluorophenyl)Vinyl Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and conjugated systems. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and material science, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura couplings to form carbon-carbon bonds, facilitating the synthesis of complex, fluorinated organic molecules.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting.

Basic Information

Product Name	trans-2-(3,5-Difluorophenyl)Vinyl Boronic Acid Pinacol Ester
CAS No.	1073354-58-1
Molecular Formula	C14H17BF2O2
Molecular Weight	266.10 g/mol
Synonyms	trans-2-(3,5-Difluorophenyl)Ethenylboronic Acid Pinacol Ester; (1E)-2-[3,5-Bis(fluoranyl)phenyl]ethenylboronic Acid Pinacol Ester; (E)-2-(3,5-Difluorophenyl)Vinylboronic Acid Pinacol Ester; B-[2-(3,5-Difluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; trans-2-(3,5-Difluorostyryl)boronic Acid Pinacol Ester; Boronic Acid, B-[2-(3,5-Difluorophenyl)ethenyl]-, 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane Ester, (1E)-; 1073354-58-1
EINECS	Contact for details

Quality Control

Our trans-2-(3,5-Difluorophenyl)Vinyl Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.