Description

n-(p-Toluenesulfonyl)Indole-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. This compound is specifically engineered for use in cross-coupling reactions, most notably the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. It is an essential reagent for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science, where precise molecular assembly is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those containing complex indole scaffolds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds under mild conditions.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Employed in the creation of organic electronic materials and functional polymers.
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and labeled compounds for biological studies.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	n-(p-Toluenesulfonyl)Indole-3-Boronic Acid Pinacol Ester
CAS No.	1073354-51-4
Molecular Formula	C21H24BNO4S
Molecular Weight	397.29 g/mol
Synonyms	1-Tosyl-1H-indole-3-boronic acid pinacol ester; 1-[(4-Methylphenyl)sulfonyl]-1H-indole-3-boronic acid pinacol ester; N-Tosylindole-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indole; 1H-Indole-3-boronic acid, 1-[(4-methylphenyl)sulfonyl]-, 1,1-dimethylethyl ester; B-[1-[(4-Methylphenyl)sulfonyl]-1H-indol-3-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our n-(p-Toluenesulfonyl)Indole-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.