Description

4-(4'-Allyloxycarbonylpiperizino)Phenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a key intermediate in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group for Suzuki-Miyaura cross-coupling reactions with a reactive allyl ester moiety, enabling further orthogonal transformations. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors who are developing complex molecules, such as active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those requiring the introduction of aryl or heteroaryl groups via palladium-catalyzed cross-coupling.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronic ester reagent for forming carbon-carbon bonds between sp2-hybridized carbons.
• Polymer & Materials Science: Used in the development of specialty polymers and functional organic materials where the allyl group can participate in thiol-ene or other click chemistry reactions.
• Ligand & Catalyst Development: Acts as a precursor for creating novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Biology & Bioconjugation: The allyloxycarbonyl (Alloc) protecting group can be selectively deprotected, making this compound useful for probe and linker synthesis.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents with complex aromatic architectures.

Basic Information

Product Name	4-(4'-Allyloxycarbonylpiperizino)Phenylboronic Acid, Pinacol Ester
CAS No.	1073354-49-0
Molecular Formula	C21H30BNO4
Molecular Weight	371.28 g/mol
Synonyms	4-(4-(Allyloxycarbonyl)piperazin-1-yl)phenylboronic acid pinacol ester; 1-Allyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-carboxylate; 4-(N-Allyloxycarbonylpiperazino)benzeneboronic acid pinacol ester; 4-(4-(Allyloxycarbonyl)-1-piperazinyl)benzeneboronic acid pinacol ester; B-[4-[4-(Allyloxycarbonyl)-1-piperazinyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1073354-49-0
EINECS	Contact for details

Quality Control

Our production of 4-(4'-Allyloxycarbonylpiperizino)Phenylboronic Acid, Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.