Description

2-(Cyclohexyloxy)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role in facilitating key carbon-carbon and carbon-heteroatom bond-forming reactions, particularly in cross-coupling methodologies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring complex pyridine-boronate structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Medicinal Chemistry: Employed in the discovery and optimization of drug candidates, particularly for creating compound libraries with high structural diversity.
• Catalyst & Ligand Development: Utilized in the preparation of novel organoboron ligands and catalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, functionalized pyridine derivatives.

Basic Information

Product Name	2-(Cyclohexyloxy)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1073354-43-4
Molecular Formula	C17H26BNO3
Molecular Weight	303.21 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(cyclohexyloxy)pyridine; 2-Cyclohexyloxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Cyclohexyloxy)pyridine-3-boronic acid pinacol ester; Pyridine, 2-(cyclohexyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1073354-43-4
EINECS	Contact for details

Quality Control

Our production of 2-(Cyclohexyloxy)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with cGMP, ICH guidelines, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.