Description

6-(4-Methylbenzylamino)Pyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules. The CAS number for this compound is 1073354-32-1.

Application

This boronic ester is a key reagent in modern synthetic chemistry, enabling the formation of carbon-carbon bonds under mild conditions.

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyridine and biphenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Research: A valuable tool in academic and industrial R&D for constructing complex molecular libraries for drug discovery and catalyst development.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	6-(4-Methylbenzylamino)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1073354-32-1
Molecular Formula	C19H25BN2O2
Molecular Weight	324.23 g/mol
Synonyms	6-[(4-Methylbenzyl)amino]pyridine-3-boronic acid pinacol ester; 6-(p-Methylbenzylamino)pyridin-3-ylboronic acid pinacol ester; 3-Borono-6-[(4-methylbenzyl)amino]pyridine pinacol ester; (6-((4-Methylbenzyl)amino)pyridin-3-yl)boronic acid pinacol ester; 1073354-32-1; BRN 12511379
EINECS	Contact for details

Quality Control

Our 6-(4-Methylbenzylamino)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. This material is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.