Description

4-(4-Isopropylpiperizinyl)Phenylboronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules. The pinacol ester group provides enhanced stability and handling characteristics compared to the free boronic acid.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds between aryl groups under mild conditions.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Development: A precursor for creating organic electronic materials, including charge-transport layers and emissive materials in OLED displays.
• Ligand Synthesis: Intermediate for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tools for studying biological systems and target engagement.

Basic Information

Product Name	4-(4-Isopropylpiperizinyl)Phenylboronic Acid, Pinacol Ester
CAS No.	1073354-18-3
Molecular Formula	C20H31BN2O2
Molecular Weight	342.29 g/mol
Synonyms	4-(4-Isopropylpiperazin-1-yl)benzeneboronic acid pinacol ester; 1-Isopropyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine; 4-(4-Isopropyl-1-piperazinyl)phenylboronic acid pinacol ester; 2-[4-(4-Isopropylpiperazin-1-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4-Isopropylpiperazinyl)phenylboronic acid pinacol ester; 4-(4-Isopropylpiperazin-1-yl)phenylboronic acid, pinanediol ester (common alternative); PINACOL 4-(4-ISOPROPYLPIPERAZIN-1-YL)BENZENEBORONATE
EINECS	Contact for details

Quality Control

Our 4-(4-Isopropylpiperizinyl)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliable consistency and traceability for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.