Description

2-Formylpyridine-5-Boronic Acid Pinacolate is a high-purity, multifunctional heterocyclic building block essential for modern synthetic chemistry. This compound is valued for its dual reactive sites, enabling its use as a key precursor in complex molecular assembly via cross-coupling and condensation reactions. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in creating kinase inhibitors and other small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester component for forming carbon-carbon bonds to construct biaryl and heterobiaryl structures.
• Ligand Synthesis for Catalysis: Used to prepare pyridine-based ligands for transition metal catalysts used in asymmetric synthesis and industrial processes.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science & OLED Development: Acts as a precursor for creating organic semiconductors, light-emitting materials, and advanced polymers.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and sensors for studying biological processes and diagnostics.

Basic Information

Product Name	2-Formylpyridine-5-Boronic Acid Pinacolate
CAS No.	1073354-14-9
Molecular Formula	C₁₃H₁₈BNO₃
Molecular Weight	247.10 g/mol
Synonyms	5-Formylpyridine-2-boronic acid pinacol ester; (5-Formylpyridin-2-yl)boronic acid pinacol ester; 2-Pyridinecarboxaldehyde-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinaldehyde; 2-Formyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(Dimethylglyoximato)boron-2-picolinaldehyde (pinacol ester); Picolinaldehyde-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Formylpyridine-5-Boronic Acid Pinacolate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.