Description

2-(tert-Butylcarbonylamino)Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in cross-coupling reactions, offering enhanced stability and handling characteristics compared to its free boronic acid counterpart. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this protected boronate ester, essential in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and activity-based protein profiling reagents.

Basic Information

Item	Detail
Product Name	2-(tert-Butylcarbonylamino)Phenylboronic Acid, Pinacol Ester
CAS No.	1073354-10-5
Molecular Formula	C₁₇H₂₆BNO₃
Molecular Weight	303.21 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]phenylboronic acid pinacol ester; N-Boc-2-aminophenylboronic acid pinacol ester; 2-(Boc-amino)phenylboronic acid pinacol ester; 2-(N-Boc-amino)phenylboronic acid pinacol ester; (2-((tert-Butoxycarbonyl)amino)phenyl)boronic acid pinacol ester; Boc-2-APin; 2-Aminophenylboronic acid pinacol ester, N-Boc protected
EINECS	Contact for details

Quality Control

Every batch of our 2-(tert-Butylcarbonylamino)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical testing including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.