Description

2-(1,3-Dioxolan-2-Yl)Ethylboronic Acid Pinacol Ester is a high-purity, protected boronic ester building block crucial for modern synthetic chemistry. This compound matters as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and bioconjugates for studying biological processes and target engagement.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in fine chemical production.

Basic Information

Product Name	2-(1,3-Dioxolan-2-Yl)Ethylboronic Acid Pinacol Ester
CAS No.	1073354-07-0
Molecular Formula	C11H21BO4
Molecular Weight	228.09 g/mol
Synonyms	2-(1,3-Dioxolan-2-yl)ethylboronic acid pinacol ester; 2-[2-(1,3-Dioxolan-2-yl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(1,3-Dioxolan-2-yl)ethylboronic acid, pinacol ester; 4,4,5,5-Tetramethyl-2-[2-(1,3-dioxolan-2-yl)ethyl]-1,3,2-dioxaborolane; (2-(1,3-Dioxolan-2-yl)ethyl)boronic acid pinacol ester; Pinacol [2-(1,3-dioxolan-2-yl)ethyl]boronate; CAS 1073354-07-0
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dioxolan-2-Yl)Ethylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full specification data are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.