Description

(3-(Bromomethyl)-4-(Trifluoromethoxy)Phenyl)Boronic Acid, Pinacol Ester is a high-value, multifunctional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing trifluoromethoxy and bromomethyl functional handles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the unique phenylboronate scaffold is incorporated.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner with aryl/vinyl halides to form biaryl and styrenyl structures under mild palladium catalysis.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis or as a precursor for functional materials.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological systems.
• Polymer and Material Science: Acts as a monomer or cross-linking agent in the synthesis of advanced polymers with specific electronic or structural properties.

Basic Information

Product Name	(3-(Bromomethyl)-4-(Trifluoromethoxy)Phenyl)Boronic Acid, Pinacol Ester
CAS No.	1073354-06-9
Molecular Formula	C14H17BBrF3O3
Molecular Weight	380.00 g/mol
Synonyms	[3-(Bromomethyl)-4-(trifluoromethoxy)phenyl]boronic acid pinacol ester; 4-(Trifluoromethoxy)-3-(bromomethyl)benzeneboronic acid pinacol ester; (3-Bromomethyl-4-trifluoromethoxyphenyl)boronic acid pinacol ester; Pinacol [3-(bromomethyl)-4-(trifluoromethoxy)phenyl]boronate; B-[3-(Bromomethyl)-4-(trifluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1073354-06-9
EINECS	Contact for details

Quality Control

Our (3-(Bromomethyl)-4-(Trifluoromethoxy)Phenyl)Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.