Description

4-tert-Butyloxycarbonylaminopyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid ester building block essential for modern synthetic chemistry. This compound matters for its role in facilitating efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to constructing complex molecules. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing pyridine and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical reagent for forming carbon-carbon bonds between aromatic rings, enabling the construction of complex molecular architectures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry campaigns.

Basic Information

Product Name	4-tert-Butyloxycarbonylaminopyridine-3-Boronic Acid Pinacol Ester
CAS No.	1073354-02-5
Molecular Formula	C₁₆H₂₅BN₂O₄
Molecular Weight	320.20 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-((tert-butoxycarbonyl)amino)pyridine; 4-((tert-Butoxycarbonyl)amino)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(Boc-amino)-3-boronopyridine pinacol ester; 4-(N-Boc-amino)pyridine-3-boronic acid pinacol ester; Boc-4-Amino-3-pyridylboronic acid pinacol ester; tert-Butyl [3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-4-yl]carbamate; N-Boc-4-amino-3-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-tert-Butyloxycarbonylaminopyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.