Description

2,5-Dichloro-4-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)pyridine is a high-purity, synthetically valuable boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient development, and functional material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated pyridine motifs.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and charge-transport materials, due to its boronate functionality.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and complex molecule construction via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Preparation: Serves as a building block for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for client-specific molecules.

Basic Information

Product Name	2,5-Dichloro-4-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)pyridine
CAS No.	1073353-98-6
Molecular Formula	C11H14BCl2NO2
Molecular Weight	273.95 g/mol
Synonyms	2,5-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dichloropyridine; 2,5-Dichloro-4-pyridineboronic acid pinacol ester; (2,5-Dichloropyridin-4-yl)boronic acid pinacol ester; 2,5-Dichloro-4-(pinacolboryl)pyridine; CAS 1073353-98-6; Pyridine, 2,5-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring specific analytical data or custom specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.