Description

1-Ethyl-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Thiourea is a sophisticated organoboron building block designed for advanced chemical synthesis. This compound matters because it combines the versatile reactivity of a pinacol boronate ester with a thiourea moiety, enabling its use as a key intermediate in cross-coupling reactions and as a functional group for molecular recognition. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules and developing new catalysts or sensors.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures for active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those requiring boronic acid/ester functionalization.
• Agrochemical Synthesis: Acts as a building block for creating new herbicides, fungicides, and insecticides with tailored properties.
• Materials Science Research: Employed in the development of organic electronic materials, polymers, and metal-organic frameworks (MOFs) due to its dual functional groups.
• Catalyst and Ligand Development: The thiourea group can act as a hydrogen-bond donor, making it useful in designing organocatalysts or ligands for asymmetric synthesis.
• Chemical Biology Probes: Utilized in creating molecular probes and sensors that leverage the specific binding affinity of the thiourea and boronate groups.

Basic Information

Item	Details
Product Name	1-Ethyl-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Thiourea
CAS No.	1073353-86-2
Molecular Formula	C₁₅H₂₃BN₂O₂S
Molecular Weight	306.23 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethylthiocarbanilide; 1-Ethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]thiourea; N-Ethyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]thiourea; (4-(3-Ethylthioureido)phenyl)boronic acid pinacol ester; ETU-Bpin; Bpin-Phenyl-Thiourea Derivative
EINECS	Contact for details

Quality Control

Our 1-Ethyl-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Thiourea is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.