Description

6-Chloro-1-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is a high-value, synthetically versatile indole-based boronic ester building block. This compound matters for its critical role in modern cross-coupling reactions, particularly the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need this intermediate for developing new active ingredients and functional molecules, where its specific substitution pattern offers precise control over the final product's properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel indole-based drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLED emitters and charge-transport layers.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic ester coupling partner to form carbon-carbon bonds with aryl/heteroaryl halides.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biological mechanism studies.
• Academic & Contract Research: Essential reagent for methodology development and complex molecule synthesis in research laboratories.

Basic Information

Item	Details
Product Name	6-Chloro-1-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	1073353-82-8
Molecular Formula	C15H19BClNO2
Molecular Weight	291.58 g/mol
Synonyms	6-Chloro-1-methyl-1H-indole-2-boronic acid pinacol ester; 2-(6-Chloro-1-methyl-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Chloro-1-methylindole-2-boronic acid pinacol ester; 1-Methyl-6-chloroindole-2-boronic acid pinacol ester; Pinacol 6-Chloro-1-methyl-1H-indole-2-boronate; 1073353-82-8; 6-Chloro-1-methyl-2-boronic acid pinacol ester indole
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.