Description

4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Naphthoic Acid is a high-purity, functionalized naphthoic acid derivative featuring a pinacol boronate ester group. This compound serves as a versatile and critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates, especially those with biaryl or extended aromatic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific aromatic frameworks.
• Material Science & OLED Development: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and light-emitting materials for electronic displays.
• Chemical Biology & Probe Design: Utilized in the synthesis of molecular probes and bioconjugates for imaging and diagnostic applications due to its reactive boronate handle.
• Academic & Contract Research: Essential for methodological development in organic synthesis and catalysis research within university and CRO laboratories.
• Polymer Chemistry: Can be incorporated into polymer backbones to introduce aromaticity and functionality for specialty high-performance plastics.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Naphthoic Acid
CAS No.	1073353-77-1
Molecular Formula	C17H21BO4
Molecular Weight	300.16 g/mol
Synonyms	1-Naphthoic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(Pinacolatoboryl)-1-naphthoic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene-1-carboxylic acid; 1-Carboxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 4-BPin-1-Naphthoic Acid (BPin = pinacol boronate); 4-(Pinacolboronato)-1-naphthoic acid; 4-(Pinacolboryl)-1-naphthoic acid
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Naphthoic Acid is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5% w/w
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.