Description

3-Chloro-2-Methoxy-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its role as a protected boronic ester derivative, enabling precise Suzuki-Miyaura cross-coupling reactions critical for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery and development pipelines.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create biaryl and heterobiaryl structures, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical and custom synthesis service providers.

Basic Information

Product Name	3-Chloro-2-Methoxy-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine
CAS No.	1073353-73-7
Molecular Formula	C12H17BClNO3
Molecular Weight	269.53 g/mol
Synonyms	3-Chloro-2-methoxypyridine-5-boronic acid pinacol ester; (3-Chloro-2-methoxypyridin-5-yl)boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-chloro-2-methoxypyridine; 3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methoxy-3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol (3-chloro-2-methoxypyridin-5-yl)boronate
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Methoxy-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.