Description

1,3-Bis(4-Boronophenyl)Urea,Bispinacol Ester is a high-purity, advanced boronic acid derivative, specifically a protected bis-boronate ester. This compound matters as a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation essential for complex molecule assembly. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, particularly Suzuki-Miyaura couplings.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring complex biaryl structures.
• Material Science Research: Serves as a monomer or linker in the creation of organic electronic materials, such as polymers for OLEDs and OFETs.
• Chemical Biology & Probe Development: Utilized in the synthesis of bioconjugation reagents and molecular probes for diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1,3-Bis(4-Boronophenyl)Urea,Bispinacol Ester
CAS No.	1073353-72-6
Molecular Formula	C25H34B2N2O5
Molecular Weight	472.17 g/mol
Synonyms	1,3-Bis(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea; Urea, N,N'-bis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; Bis(4-pinacolatoboronophenyl)urea; 1,3-Di(4-boronophenyl)urea bis(pinacol) ester; 4,4'-(Carbonylbis(azanediyl))dibenzeneboronic acid bis(pinacol) ester
EINECS	Contact for details

Quality Control

Our 1,3-Bis(4-Boronophenyl)Urea,Bispinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.