Description

3-(Piperidine-1-Carbonyl)Phenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected boronic acid building block in modern organic synthesis, offering enhanced stability and handling characteristics compared to its free acid form. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a versatile building block in the research and development of new drug candidates, particularly for kinase inhibitors and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific aryl-boronate intermediates.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and OFETs, where precise molecular assembly is critical.
• Chemical Biology & Proteomics: Acts as a functional handle in the synthesis of chemical probes and affinity tags for studying protein function and interactions.
• Scale-up Process Chemistry: The pinacol ester's stability makes it suitable for multi-step synthesis and larger-scale manufacturing processes in fine chemical production.

Basic Information

Product Name	3-(Piperidine-1-Carbonyl)Phenylboronic Acid, Pinacol Ester
CAS No.	1073353-62-4
Molecular Formula	C18H26BNO3
Molecular Weight	315.22 g/mol
Synonyms	[3-(Piperidine-1-carbonyl)phenyl]boronic acid pinacol ester; 3-(Piperidine-1-carbonyl)benzeneboronic acid pinacol ester; (3-(Piperidine-1-carbonyl)phenyl)boronic acid pinacol ester; Pinacol 3-(piperidine-1-carbonyl)phenylboronate; 3-(N-Piperidinylcarbonyl)phenylboronic acid pinacol ester; CAS 1073353-62-4; B-[3-(1-Piperidinylcarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of our 3-(Piperidine-1-Carbonyl)Phenylboronic Acid, Pinacol Ester is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency to meet the rigorous demands of research and development. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.