Description

4-(2-Methoxyethylaminocarbonyl)Benzeneboronic Acid Pinacol Ester is a sophisticated boronic ester derivative, a key intermediate in modern synthetic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for use in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for constructing complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating biaryl and heterobiaryl structures via Suzuki-Miyaura cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-boronate functionalities.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents that target serine hydrolases and other enzymes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-(2-Methoxyethylaminocarbonyl)Benzeneboronic Acid Pinacol Ester
CAS No.	1073353-60-2
Molecular Formula	C₁₆H₂₄BNO₄
Molecular Weight	305.18 g/mol
Synonyms	[4-(2-Methoxyethylcarbamoyl)phenyl]boronic acid pinacol ester; 4-(2-Methoxyethylaminocarbonyl)phenylboronic acid pinacol ester; N-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 4-Carbamoylbenzeneboronic acid pinacol ester, 2-Methoxyethyl derivative; B-[4-[[(2-Methoxyethyl)amino]carbonyl]phenyl]boronic acid pinacol ester; Pinacol 4-[(2-Methoxyethyl)carbamoyl]benzeneboronate
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyethylaminocarbonyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.