Description

4-(n-Methylsulfamoyl)Phenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing sulfonamide and arylboronate functional groups.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds with aryl or vinyl halides, enabling the construction of complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-sulfonamide motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is critical.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Acts as a linker or component in the design of bifunctional molecules for targeted protein degradation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	4-(n-Methylsulfamoyl)Phenylboronic Acid Pinacol Ester
CAS No.	1073353-47-5
Molecular Formula	C14H22BNO4S
Molecular Weight	311.21 g/mol
Synonyms	4-(Methylsulfamoyl)phenylboronic acid pinacol ester; [4-(Methylsulfamoyl)phenyl]boronic acid pinacol ester; 4-(N-Methylsulfamoyl)benzeneboronic acid pinacol ester; B-[4-(Methylsulfamoyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-(N-methylsulfamoyl)phenyl]-1,3,2-dioxaborolane; 4-(Methylsulfonylamino)phenylboronic acid pinacol ester; (4-(N-Methylsulfamoyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(n-Methylsulfamoyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full analytical data are provided for every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.