Description

2-(3-(Chloromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a pinacol boronic ester derivative, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This compound is critically needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for the efficient synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or substituted phenyl structures.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the 3-(chloromethyl)phenyl moiety into complex molecular frameworks.
• Material Science: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers where precise molecular architecture is required.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for methodology development and the construction of compound libraries for screening.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific aryl group introductions.

Basic Information

Item	Details
Product Name	2-(3-(Chloromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073353-44-2
Molecular Formula	C13H18BClO2
Molecular Weight	252.54 g/mol
Synonyms	(3-(Chloromethyl)phenyl)boronic acid pinacol ester; 3-(Chloromethyl)benzeneboronic acid pinacol ester; 1-(Chloromethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 2-(3-Chloromethylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; (3-Chloromethylphenyl)boronic acid, pinacol ester; 3-(Pinacolatoboryl)benzyl chloride
EINECS	Contact for details

Quality Control

Our 2-(3-(Chloromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.