Description

4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene is a high-value organoboron building block, specifically a thiophene-substituted boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates containing thiophene or biaryl motifs, particularly in kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the incorporation of heterocyclic systems.
• Organic Electronic Materials: Serves as a precursor for π-conjugated polymers and small molecules used in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create fluorescent probes, bioconjugates, and other tools for biological imaging and target identification.
• Polymer & Specialty Chemical Modification: Acts as a functional monomer or coupling agent to introduce thiophene units into polymer backbones or specialty chemical structures.

Basic Information

Product Name	4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene
CAS No.	1073339-22-6
Molecular Formula	C11H17BO3S
Molecular Weight	240.13 g/mol
Synonyms	2-(4-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxy-2-thienylboronic acid pinacol ester; 2-(4-Methoxy-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxythiophene-2-boronic acid pinacol ester; 2-(4-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxy-2-thiopheneboronic acid pinacol ester; 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 2-(4-Methoxy-thiophen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity (by HPLC/NMR), identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.