Description

4,4,5,5-Tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane is a high-purity, fluorinated boronic ester derivative, serving as a critical advanced synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heteroaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it facilitates the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides with enhanced efficacy and environmental profiles.
• Materials Science: Precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands and organometallic catalysts.
• Chemical Biology Probes: Enables the site-specific labeling and modification of biomolecules for diagnostic and research applications.
• Polymer Chemistry: Incorporated into polymer backbones to impart unique thermal, optical, or solubility properties.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane
CAS No.	1073339-11-3
Molecular Formula	C12H13BF4O2
Molecular Weight	276.04 g/mol
Synonyms	2-(2,3,5,6-Tetrafluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(Perfluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (common name for tetrafluoro substitution pattern); Pinacol (2,3,5,6-tetrafluorophenyl)boronate; Tetrafluorophenylpinacolboronate; (2,3,5,6-Tetrafluorophenyl)boronic acid pinacol ester; 1073339-11-3; B-(2,3,5,6-Tetrafluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 4,4,5,5-Tetramethyl-2-(2,3,5,6-tetrafluorophenyl)-1,3,2-dioxaborolane adheres to a stringent quality management system. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.