Description

2-(Benzo[D][1,3]Dioxol-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing benzodioxole motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-boron coupling partners.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and complex molecule construction via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty and performance chemicals where precise molecular architecture is required.

Basic Information

Product Name	2-(Benzo[D][1,3]Dioxol-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073339-10-2
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzodioxole; 1,3-Benzodioxol-4-ylboronic acid pinacol ester; 4-(Pinacolatoboryl)-1,3-benzodioxole; Benzo[d][1,3]dioxol-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d][1,3]dioxole; Pinacol 1,3-benzodioxol-4-ylboronate
EINECS	Contact for details

Quality Control

Our 2-(Benzo[D][1,3]Dioxol-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance in sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.