Description

3-Chloro-4-Formylphenylboronic Acid is a versatile bifunctional building block that combines a formyl group and a boronic acid moiety on a chlorinated aromatic ring. This compound matters for its critical role in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling, enabling the efficient construction of complex molecules. Pharmaceutical researchers, agrochemical developers, and material scientists need it as a key intermediate for creating advanced active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and boronic acid functionalities for structural diversification.
• Material Science & OLED Development: Serves as a building block for creating advanced organic electronic materials, including charge-transport layers and emissive materials in OLED displays.
• Ligand & Catalyst Design: The formyl group allows for further functionalization to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Bioconjugation: Utilized in probe and linker synthesis for studying biological processes and developing antibody-drug conjugates (ADCs).
• Polymer & Resin Modification: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with tailored properties.

Basic Information

Product Name	3-Chloro-4-Formylphenylboronic Acid
CAS No.	1072952-53-4
Molecular Formula	C7H6BClO3
Molecular Weight	184.38 g/mol
Synonyms	(3-Chloro-4-formylphenyl)boronic acid; 4-Borono-2-chlorobenzaldehyde; 2-Chloro-4-boronobenzaldehyde; 3-Chloro-4-formylbenzeneboronic acid; 2-Chloro-4-formylphenylboronic acid; Boronic acid, B-(3-chloro-4-formylphenyl)-; 3-Chloro-4-carboxaldehydephenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.