Description

2,4-Dichloropyridine-5-Boronic Acid Hydrate is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require a reliable, high-purity intermediate for developing active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, antiviral agents, and other heterocyclic drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require the 2,4-dichloropyridine scaffold.
• Material Science: Precursor for creating organic electronic materials, such as ligands for OLEDs (Organic Light-Emitting Diodes) and components for molecular sensors.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic routes and creating complex molecular libraries.
• Ligand Synthesis: Used to prepare sophisticated boronic acid-based ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	2,4-Dichloropyridine-5-Boronic Acid Hydrate
CAS No.	1072952-26-1
Molecular Formula	C5H5BCl2NO3 (Anhydrous basis: C5H4BCl2NO2)
Molecular Weight	207.82 g/mol (Anhydrous basis)
Synonyms	(5-Borono-2,4-dichloropyridine) Hydrate; 2,4-Dichloro-5-pyridineboronic acid hydrate; 5-Borono-2,4-dichloropyridine hydrate; (2,4-Dichloropyridin-5-yl)boronic acid hydrate; 2,4-Dichloro-5-pyridinylboronic acid hydrate; B-(2,4-Dichloro-5-pyridinyl)boronic acid hydrate
EINECS	Contact for details

Quality Control

Our 2,4-Dichloropyridine-5-Boronic Acid Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Boronic Acid)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.