Description

3-[(4-Chloro-3-Methylphenoxy)Methyl]Phenylboronic Acid CAS NO 1072951-91-7 is a specialized organoboron compound featuring a chloromethylphenoxy-substituted phenyl ring, making it a valuable boronic acid derivative for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the creation of organic electronic materials, polymers, and liquid crystals where the boronic acid functional group is essential.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and sensors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories worldwide.

Basic Information

Product Name	3-[(4-Chloro-3-Methylphenoxy)Methyl]Phenylboronic Acid
CAS No.	1072951-91-7
Molecular Formula	C14H14BClO3
Molecular Weight	276.52 g/mol
Synonyms	[4-Chloro-3-methylphenoxy)methyl]benzeneboronic acid; (3-((4-Chloro-3-methylphenoxy)methyl)phenyl)boronic acid; 3-((4-Chloro-3-methylphenoxy)methyl)benzeneboronic acid; Boronic acid, B-[3-[[(4-chloro-3-methylphenyl)oxy]methyl]phenyl]-; 3-[(4-Chloro-3-methyl-phenoxy)methyl]-phenylboronic acid; 3-((4-Chloro-m-tolyloxy)methyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-[(4-Chloro-3-Methylphenoxy)Methyl]Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.