Description

2-Methoxy-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl-substituted pyridine motifs, which are prevalent in drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as ligands for catalysts or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of molecular probes and tool compounds for target validation and biochemical pathway studies.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid
CAS No.	1072946-55-4
Molecular Formula	C8H7BF3NO3
Molecular Weight	233.95 g/mol
Synonyms	2-Methoxy-5-(trifluoromethyl)pyridine-3-boronic acid; [2-Methoxy-5-(trifluoromethyl)-3-pyridinyl]boronic acid; 3-Borono-2-methoxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-methoxypyridine-3-boronic acid; 2-Methoxy-5-trifluoromethyl-3-pyridineboronic acid; 3-Pyridineboronic acid, 2-methoxy-5-(trifluoromethyl)-; Boronic acid, B-[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.