Description

3,4,5-Trichloro-2-Methylphenylboronic Acid is a specialized organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting complex, multi-substituted aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated phenyl motifs for enhanced activity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for catalysts or monomers for conductive polymers, where the trichloro-methylphenyl group modifies electronic properties.
• Chemical Synthesis: Functions as a versatile boronic acid reagent in palladium-catalyzed cross-coupling reactions to create custom-designed biaryl and heterobiaryl compounds for various R&D applications.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	3,4,5-Trichloro-2-Methylphenylboronic Acid
CAS No.	1072946-34-9
Molecular Formula	C7H6BCl3O2
Molecular Weight	243.29 g/mol
Synonyms	(3,4,5-Trichloro-2-methylphenyl)boronic acid; 2-Methyl-3,4,5-trichlorobenzeneboronic acid; Boronic acid, B-(3,4,5-trichloro-2-methylphenyl)-; 3,4,5-Trichloro-o-tolylboronic acid; 1072946-34-9; (3,4,5-Trichloro-2-tolyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3,4,5-Trichloro-2-Methylphenylboronic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.