Description

4-(1-Boc-Piperidin-4-Yloxy)-2-Methoxyphenylboronic is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine moiety and a boronic acid functional group. This compound is critical for modern medicinal chemistry, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction to construct complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new drug candidates, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for creating carbon-carbon bonds in complex organic synthesis.
• Protease Inhibitor Research: Used in the development of compounds targeting proteases, leveraging the piperidine scaffold.
• Kinase Inhibitor Libraries: Integral to the construction of diverse compound libraries for high-throughput screening against kinase targets.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Suitable for route scouting and optimization during the transition from laboratory to pilot-scale manufacturing.

Basic Information

Product Name	4-(1-Boc-Piperidin-4-Yloxy)-2-Methoxyphenylboronic
CAS No.	1072946-29-2
Molecular Formula	C18H28BNO5
Molecular Weight	349.23 g/mol
Synonyms	4-(1-Boc-Piperidin-4-Yloxy)-2-Methoxyphenylboronic Acid; 2-Methoxy-4-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]phenylboronic Acid; 4-(1-Boc-4-Piperidyloxy)-2-Methoxyphenylboronic Acid; 4-(1-(tert-Butoxycarbonyl)piperidin-4-yloxy)-2-methoxyphenylboronic Acid; 4-(N-Boc-piperidin-4-yloxy)-2-methoxybenzeneboronic Acid; B-[4-[(1-[(1,1-Dimethylethoxy)carbonyl]-4-piperidinyl)oxy]-2-methoxyphenyl]-Boronic Acid; 1072946-29-2
EINECS	Contact for details

Quality Control

Our 4-(1-Boc-Piperidin-4-Yloxy)-2-Methoxyphenylboronic is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.