Description

Bis(3,4-Dimethylphenyl)(Hydroxy)Borane CAS NO 1072946-23-6 is a specialized organoboron compound featuring a hydroxyborane functional group flanked by two 3,4-dimethylphenyl substituents. This structure makes it a valuable intermediate in advanced organic synthesis, particularly for the construction of complex molecules and materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and as a precursor to novel boron-containing compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a key boron reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new drug candidates, particularly those requiring specific aryl-boron functionalities.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the dimethylphenyl-borane moiety imparts desired biological activity or stability.
• Materials Science Research: Employed as a precursor for developing advanced materials, such as organic semiconductors, luminescent compounds, or polymeric materials with tailored properties.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands for transition metal catalysts used in homogeneous catalysis.
• Academic and Industrial R&D: A valuable tool for synthetic chemists in both university laboratories and corporate R&D centers exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	Bis(3,4-Dimethylphenyl)(Hydroxy)Borane
CAS No.	1072946-23-6
Molecular Formula	C16H19BO
Molecular Weight	238.14 g/mol
Synonyms	Hydroxybis(3,4-dimethylphenyl)borane; (Hydroxy)bis(3,4-dimethylphenyl)borane; Bis(3,4-dimethylphenyl)borinic acid; 3,4-Dimethylphenylboronic acid, anhydride; Dihydroxybis(3,4-dimethylphenyl)borane (dimer form); B-(3,4-Dimethylphenyl)-B-hydroxyborane; (3,4-Xylyl)hydroxyborane dimer
EINECS	Contact for details

Quality Control

Our Bis(3,4-Dimethylphenyl)(Hydroxy)Borane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container must be kept tightly sealed in a dry environment to minimize exposure to moisture and oxygen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.