Description

1-p-Tolylpyrazole-4-Boronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who are developing novel active ingredients and functional molecules. Its specific structure enables the synthesis of complex pyrazole-containing targets with high efficiency and selectivity.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing heterocyclic pyrazole cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific pyrazole motifs for biological activity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic routes and creating compound libraries via cross-coupling.
• Ligand Synthesis: Can be utilized to construct sophisticated polydentate ligands for coordination chemistry and catalysis.

Basic Information

Product Name	1-p-Tolylpyrazole-4-Boronic Acid
CAS No.	1072945-92-6
Molecular Formula	C10H11BN2O2
Molecular Weight	202.02 g/mol
Synonyms	1-(4-Methylphenyl)-1H-pyrazole-4-boronic acid; 1-(p-Tolyl)-1H-pyrazole-4-boronic acid; 4-Borono-1-p-tolylpyrazole; 1-(4-Methylphenyl)-4-boronopyrazole; 1-(4-Methylphenyl)-1H-pyrazole-4-boronic Acid Pinacol Ester (common protected form); 1-p-Tolyl-1H-pyrazole-4-boronic Acid; B-[1-(4-Methylphenyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-p-Tolylpyrazole-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and other relevant assays to ensure it meets the high standards required for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.