Description

1-(2-Chlorophenyl)Pyrazole-4-Boronic Acid is a high-purity boronic acid derivative, a key building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial synthon for constructing novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Research: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Ligand & Catalyst Development: Employed in the synthesis of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: Potential use in bioconjugation chemistry for labeling biomolecules due to its boronic acid functionality.

Basic Information

Product Name	1-(2-Chlorophenyl)Pyrazole-4-Boronic Acid
CAS No.	1072945-91-5
Molecular Formula	C9H8BClN2O2
Molecular Weight	222.44 g/mol
Synonyms	(2-Chlorophenyl)-1H-pyrazol-4-ylboronic acid; 1-(2-Chlorophenyl)-1H-pyrazole-4-boronic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-chlorophenyl)-1H-pyrazole; 1-(2-Chlorophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(2-Chlorophenyl)pyrazole-4-boronic acid pinacol ester; 1-(o-Chlorophenyl)pyrazole-4-boronic acid; B-[1-(2-Chlorophenyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)Pyrazole-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.