Description

1-(3-Chlorophenyl)Pyrazole-4-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize complex molecules for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, herbicides, and fungicides that require specific chlorophenyl-pyrazole motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(3-Chlorophenyl)Pyrazole-4-Boronic Acid
CAS No.	1072945-88-0
Molecular Formula	C9H8BClN2O2
Molecular Weight	222.43 g/mol
Synonyms	[4-(3-Chlorophenyl)-1H-pyrazol-1-yl]boronic acid; (1-(3-Chlorophenyl)-1H-pyrazol-4-yl)boronic acid; 1-(3-Chlorophenyl)-1H-pyrazole-4-boronic acid; 3-Chlorophenylpyrazole-4-boronic acid; 1-(3-Chlorophenyl)-4-pyrazoleboronic acid; B-[1-(3-Chlorophenyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Chlorophenyl)Pyrazole-4-Boronic Acid is produced under strict quality management protocols. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR/Titration)	≥95.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.