Description

4-Hydroxy-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound matters as a critical building block for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions, offering enhanced stability and handling compared to its free boronic acid counterpart. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in creating new herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science & OLED Development: Serves as a precursor for constructing conjugated organic molecules used in organic light-emitting diodes (OLEDs) and electronic materials.
• Ligand & Catalyst Synthesis: Employed in the preparation of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and sensors for biological target identification and validation.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Hydroxy-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	1072945-08-4
Molecular Formula	C12H16BNO5
Molecular Weight	265.07 g/mol
Synonyms	2-(4-Hydroxy-3-nitrophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Hydroxy-3-nitrobenzeneboronic Acid Pinacol Ester; (4-Hydroxy-3-nitrophenyl)boronic Acid Pinacol Ester; 3-Nitro-4-hydroxyphenylboronic Acid Pinacol Ester; Pinacol (4-Hydroxy-3-nitrophenyl)boronate; 1072945-08-4; 4-Hydroxy-3-nitrophenyl-Bpin
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Nitrophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.