Description

4-Methyl-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing substituted biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Material Science Research: Utilized in the development of organic electronic materials, such as OLEDs and semiconductors, where controlled conjugation is needed.
• Chemical Biology Probes: Serves as a building block for creating molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Item	Details
Product Name	4-Methyl-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	1072945-06-2
Molecular Formula	C13H18BNO4
Molecular Weight	263.10 g/mol
Synonyms	3-Nitro-4-methylbenzeneboronic Acid Pinacol Ester; (3-Nitro-4-methylphenyl)boronic Acid Pinacol Ester; 4-Methyl-3-nitrophenylboronic Acid Pinanediol Ester; 2-(4-Methyl-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (4-Methyl-3-nitrophenyl)boronate; Boronic acid, B-(4-methyl-3-nitrophenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-3-Nitrophenylboronic Acid, Pinacol Ester is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profiles are provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.