Description

(E)-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylic Acid is a high-purity boronic ester derivative featuring an acrylic acid functional group, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, enabling efficient cross-coupling reactions for constructing complex organic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with complex, targeted molecular structures.
• Material Science: Building block for organic electronic materials, including polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organoboron catalysts.
• Chemical Biology Probes: Utilized in the development of molecular probes and bioconjugation agents for diagnostic and research applications.
• Academic & Industrial R&D: Fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	(E)-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylic Acid
CAS No.	1072944-97-8
Molecular Formula	C₁₅H₁₉BO₄
Molecular Weight	274.12 g/mol
Synonyms	(E)-3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acrylic acid; 4-(2-Carboxyvinyl)phenylboronic acid pinacol ester; trans-3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]prop-2-enoic acid; 4-Acrylic acid phenylboronic acid pinacol ester; 1072944-97-8; Boric acid, B-[4-[(1E)-2-carboxyethenyl]phenyl]-, 2,2-dimethyl-1,3-propanediyl ester
EINECS	Contact for details

Quality Control

Our (E)-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.