Description

4-Chlorobenzonitrile-2,5-Diboronic Acid Neopentyl Glycol Ester is a high-purity, multi-functional boronic acid ester building block designed for advanced organic synthesis. This compound is critical for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials, due to its dual boronate functionality and protected ester form. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific chlorobenzonitrile motifs.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Research: An essential reagent in academic and industrial R&D for exploring new catalytic cross-coupling methodologies and constructing complex organic molecules.
• Ligand Synthesis: Used to prepare sophisticated boronate-containing ligands for catalysis and sensor development.

Basic Information

Product Name	4-Chlorobenzonitrile-2,5-Diboronic Acid Neopentyl Glycol Ester
CAS No.	1072944-28-5
Molecular Formula	C₁₄H₁₈B₂ClNO₄
Molecular Weight	328.76 g/mol
Synonyms	2,5-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-chlorobenzonitrile; 4-Chloro-2,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 4-Chloro-2,5-di(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2,5-Diboronic Acid Neopentyl Glycol Ester of 4-Chlorobenzonitrile; Pinacol ester of 4-Chloro-2,5-diboronobenzoic acid nitrile; 1072944-28-5; 4-Chloro-2,5-bis(pinacolatoboryl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Chlorobenzonitrile-2,5-Diboronic Acid Neopentyl Glycol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.