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D-Tarb-No2, 2-(3-Nitrophenyl)-1,3,2-Dioxaborolane-4S,5S-Dicarboxylic Acid CAS NO 1072944-27-4
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CAS No.:1072944-27-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-Tarb-No2, 2-(3-Nitrophenyl)-1,3,2-Dioxaborolane-4S,5S-Dicarboxylic Acid is a high-value, stereochemically defined boronic ester derivative, serving as a critical chiral building block in modern organic synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, which is essential for developing pharmaceuticals and advanced materials. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and cross-coupling reactions.
Application
- Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
- Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, air- and moisture-tolerant organoboron reagent for forming carbon-carbon bonds with high enantiomeric purity.
- Asymmetric Catalysis: Used as a ligand or auxiliary in catalytic systems to induce chirality in target molecules.
- Agrochemical Research: Building block for developing novel, stereospecific herbicides, fungicides, and insecticides.
- Material Science: Precursor for creating chiral polymers or organic frameworks with unique optical or electronic properties.
- Academic & Industrial R&D: Essential tool compound for methodological development in synthetic organic chemistry laboratories.
Basic Information
| Product Name | D-Tarb-No2, 2-(3-Nitrophenyl)-1,3,2-Dioxaborolane-4S,5S-Dicarboxylic Acid |
| CAS No. | 1072944-27-4 |
| Molecular Formula | C11H10BNO8 |
| Molecular Weight | 295.01 g/mol |
| Synonyms | (4S,5S)-2-(3-Nitrophenyl)-1,3,2-dioxaborolane-4,5-dicarboxylic acid; 2-(3-Nitrophenyl)-4,5-O-isopropylidene-D-tartaric boronic ester; D-Tartaric Acid Boronic Ester Nitro Derivative; (4S,5S)-4,5-Dicarboxy-2-(3-nitrophenyl)-1,3,2-dioxaborolane; D-Tartaric Acid Derived Nitrophenylboronate; TADDOL-type Nitrophenyl Boronate; Chiral Nitrophenylboronic Ester; D-Tarb-NO2 Boronic Acid Ester |
| EINECS | Contact for details |
Quality Control
Every batch of D-Tarb-No2 is produced under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific tests such as chiral HPLC, NMR, and elemental analysis are available upon request to support your quality assurance and regulatory documentation.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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